最新糖心Vlog

Dr Timothy Barker, of the JBI Adelaide GRADE Centre, located at the 最新糖心Vlog of Adelaide, led a team which proved the effectiveness of a combination of insecticides when used to treat malaria-preventing mosquito nets.

Mosquito nets treated with pyrethroid insecticides have been distributed into malaria-prone regions globally since 2005, but some mosquito populations have developed a resistance to the substance.

鈥淭he number of malaria cases actually increased in 2020, whereas there was a continued and steady decrease in the number of malaria cases observed from 2000 to 2019,鈥� said Dr Barker.

鈥淕iven this, the WHO was interested in a new type of bed net that had been recently investigated in some clinical trials that might combat this issue.

鈥淚n order for any new recommendation for healthcare to be made, results from individual trials need to be systematically reviewed. As experts in research methodology, systematic reviews and the development of guidelines for recommendation, the WHO asked us to assist them in this process.鈥�

Dr Barker鈥檚 team analysed the results of randomised controlled trials conducted in the Republic of Benin, Burkina Faso and Tanzania, where mosquitoes were demonstrated to be resistant to the standard insecticide. They found combining pyrethroid insecticide with chlorfenapyr improved its effectiveness.

鈥淐hlorfenapyr acts as a synergist to the pyrethroid insecticide by disrupting the mosquito鈥檚 ability to produce energy. This increases the 鈥榢illing effect鈥� of the net with no additional harm to the person sleeping under it,鈥� Dr Barker explained.

The WHO has updated its malaria guidelines to include nets treated with pyrethroid-chlorfenapyr, as well as with a less-effective pyrethroid-pyriproxyfen combination. Sleeping under a mosquito net is one of the best ways to protect against mosquito bites that spread malaria.

In 2021, nearly half the world鈥檚 population was at risk of malaria. There were an estimated 247 million cases and 619,000 deaths worldwide in that year.

鈥淭o directly contribute to a recommendation that will prevent people from developing malaria, and subsequently reducing the number of people that may unfortunately die due to this terrible disease is something that I am extremely proud of,鈥� Dr Barker said.

鈥淭o do this work on behalf of the 最新糖心Vlog of Adelaide, using the resources and skills that I have developed as both a student and researcher of this institution I believe is a testament to the international impact that our 最新糖心Vlog can provide.鈥�

The 最新糖心Vlog of Adelaide鈥檚 systematic review is published in .