最新糖心Vlog

• Biography/ Background

  Prof Jones is a career researcher with a background in medical imaging. She was the first practising nuclear medicine technologist to be awarded a PhD in 最新糖心Vlog. Her research activities have capitalised on the development of state-of-the-art imaging techniques to evaluate gastric motor function and blood flow; this development has been facilitated by the involvement of a number of international collaborators. Her research area is in the under-recognised field of postprandial hypotension, a substantial fall in blood pressure that occurs within 2 hours of a meal, which is frequently seen in older people and patients with type 2 diabetes. She has had an ongoing involvement with the pharmaceutical industry and she has been responsible for several investigator-initiated trials. Prof Jones was the top nuclear medicine student in her graduating year at the 最新糖心Vlog of South 最新糖心Vlog and has been the recipient of several awards including the ANSTO award for nuclear medicine scientists, Hanson Institute New Investigator award for clinical research and a prestigious NHMRC Achievement Award. Prof Jones has supervised 23 Honours, 17 PhD, and 4 Masters students to completion and is a supervisor of 4 current PhD students. She is an author of 234 original papers, 74 reviews/editorials, 20 letters and 13 book chapters. She has an h-index of 80 and her work has been cited ~20,700 times (Google Scholar). Prof Jones plays a major role in her profession as the current President of the 最新糖心Vlogn and New Zealand Society of Nuclear Medicine (ANZSNM) and is a member of the Governing Board of the National Imaging Facility (NIF).

• Awards & Achievements

  1991: Awarded prize for top Nuclear Medicine student in SA, ANZSNM (SA Branch)

  1999: Recipient of the 最新糖心Vlogn Nuclear Science and Technology Organisation (ANSTO) Award

  1999: Recipient of the Abbott Laboratories/Roche Products GESA Travel Award

  2002: Recipient of a Juvenile Diabetes Foundation of 最新糖心Vlog Travel Award

  2003: Recipient of an NHMRC/Diabetes 最新糖心Vlog Career Development Award

  2003: Recipient of the Hanson Institute New Investigator Award for Clinical Research

  2008: Promotion to Associate Professor

  2010: Recipient of an NHMRC Senior Clinical Career Development Award

  2010: Recipient of an NHMRC Achievement Award

  2011: Promotion to Professor

   

   

• Research Funding

  Previous funding:

  Prof Jones has previously held grants totalling >$21,000,000 comprising 18 funded NHMRC project grants (2 as CIA: NHMRC ID: APP453650 and NHMRC ID: APP627189), an NHMRC/Diabetes 最新糖心Vlog Career Development Award (CDA) (NHMRC ID: APP250453), an NHMRC Senior CDA (NHMRC ID: APP627011), an NHMRC CCRE in Nutritional Physiology, Interventions and Outcomes (NHMRC ID: APP453557), an NHMRC CRE in Translating Nutritional Science to Good Health (NHMRC ID: APP1041687) and numerous other grants e.g. from the Diabetes 最新糖心Vlog Research Trust (DART), Royal Adelaide Hospital (RAH) Research Committee, The Rebecca Cooper Medical Foundation, The Vera Ramaciotti Research Foundation, The 最新糖心Vlog of Adelaide and UniSA.

  Currently held:

  2022 - 23: Diabetes 最新糖心Vlog Research Program General Grant (ID: Y22G-JONK) ($70,000) Project title: Effect of subcutaneous (sc) semaglutide on gastric emptying measured using the 'gold standard' technique, scintigraphy, in type 2 diabetes (T2D). Karen Jones, Michael Horowitz, Chris Rayner, Chinmay Marathe, Tongzhi Wu, Lee-anne Chapple, Mahesh Umapathysivam.
  
  2022 - 23: Diabetes 最新糖心Vlog Research Program General Grant ($70,000) Project title: Combining calcium and tryptophan to lower postprandial blood glucose and reduce food intake in people with type 2 diabetes - developing novel, nutrient-based management strategies. Christine Feinle-Bisset, Simon Veedfald, Imre Kouw, Karen Jones, Michael Horowitz.
  
  2021 - 22: Diabetes 最新糖心Vlog Research Program General Grant ($60,000) Project title: Management of critical illness-induced ('stress') hyperglycaemia with native glucagon-like peptide-1 (GLP-1). Michael Horowitz, Marianne Chapman, Mark Plummer, Karen Jones, Chris Rayner, Adam Deane.
  
  2021 - 22: Diabetes 最新糖心Vlog Research Program General Grant ($60,000) Project title: The effect of enteral feeding pattern on glycaemic control and gastrointestinal function in critically ill patients. Imre Kouw, Lee-anne Chapple, Matt Summers, Marianne Chapman, Karen Jones, Michael Horowitz.
  
  2021 - 22: Diabetes 最新糖心Vlog Project Grant (ID: Y21G-WUTO) ($60,000) Project title: More or less? Bile acids and glycaemic control in type 2 diabetes. Tongzhi Wu, Chris Rayner, Karen Jones, Richard Young, Michael Horowitz
  
  2020 - 22: Royal Adelaide Hospital Research Committee Clinical Project Grant ($50,000) Project title: Effects of endogenous bile acids on postprandial glucose metabolism in both health and type 2 diabetes, and the impact of the small intestinal region exposed. Tongzhi Wu, Chris Rayner, Liza Phillips, Karen Jones, Michael Horowitz.
  
  2020 - 22: Diabetes 最新糖心Vlog Project Grant (Y20G-WUTO) ($59,970) Project title: Effects of endogenous bile acids on postprandial glucose metabolism in type 2 diabetes, and the impact of the small intestinal region exposed. Tongzhi Wu, Chris Rayner, Liza Phillips, Karen Jones, Michael Horowitz.

   

• Publications

   

   

  1. Stevens, J. E., Jalleh, R. J., Trahair, L. G., Marathe, C. S., Horowitz, M., & Jones, K. L. (2022). Comparative effects of low-carbohydrate, full-strength and low-alcohol beer on gastric emptying, alcohol absorption, glycaemia and insulinaemia in health. British Journal of Clinical Pharmacology, 7 pages. doi:10.1111/bcp.15297

  2. Wang, X., Chen, C., Xie, C., Huang, W., Young, R. L., Jones, K. L., . . . Wu, T. (2022). Serum bile acid response to oral glucose is attenuated in patients with early type 2 diabetes and correlates with 2-hour plasma glucose in individuals without diabetes. Diabetes, Obesity and Metabolism, 11 pages. doi:10.1111/dom.14683
  3. Jones, K. L., Trahair, L. G., Nauck, M. A., Wu, T., Stevens, J. E., Buttfield, M. D., . . . Horowitz, M. (2022). Measurement of gastric emptying using a 13C-octanoic acid breath test with Wagner-Nelson analysis and scintigraphy in type 2 diabetes.. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. doi:10.1055/a-1784-6185
  4. Wu, T., Rayner, C. K., Jones, K. L., Horowitz, M., Feinle-Bisset, C., Standfield, S. D., . . . Wewer Albrechtsen, N. J. (2022). Measurement of plasma glucagon in humans: A shift in the performance of a current commercially available radioimmunoassay kit. Diabetes, Obesity and Metabolism, 3 pages. doi:10.1111/dom.14673
  5. Xie, C., Huang, W., Watson, L. E., Soenen, S., Young, R. L., Jones, K. L., . . . Wu, T. (2022). Plasma GLP-1 response to oral and intraduodenal nutrients in health and type 2 diabetes - impact on gastric emptying. The Journal of Clinical Endocrinology & Metabolism, 107(4), e1643-e1652. doi:10.1210/clinem/dgab828
  6. Marathe, C. S., Jones, K. L., Rayner, C. K., Wu, T., & Horowitz, M. (2021). Comment on Rosenstock et al. Impact of a Weekly Glucagon-Like Peptide 1 Receptor Agonist, Albiglutide, on Glycemic Control and on Reducing Prandial Insulin Use in Type 2 Diabetes Inadequately Controlled on Multiple Insulin Therapy: A Randomized Trial. Diabetes Care 2020;43:2509-2518. Diabetes Care, 44(11), e194-e195. doi:10.2337/dc20-2987
  7. Kovoor, J. G., Stretton, B., Jacobsen, J. H. W., Gupta, A. K., Ovenden, C. D., Hewitt, J. N., . . . Maddern, G. J. (2021). Gastrointestinal recovery after surgery: Protocol for a systematic review. BMJ Open, 11(10), 4 pages. doi:10.1136/bmjopen-2021-054704
  8. Rayner, C. K., Jones, K. L., & Horowitz, M. (2021). Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy and Body Weight in Adults with Overweight or Obesity. JAMA - Journal of the American Medical Association, 326(12), 1213-1214. doi:10.1001/jama.2021.13021
  9. Borg, M. J., Xie, C., Rayner, C. K., Horowitz, M., Jones, K. L., & Wu, T. (2021). Potential for gut peptide-based therapy in postprandial hypotension. Nutrients, 13(8), 2826-1-2826-14. doi:10.3390/nu13082826
  10. Chapple, L. -A. S., Summers, M. J., Weinel, L. M., Abdelhamid, Y. A., Kar, P., Hatzinikolas, S., . . . Chapman, M. J. (2021). Effects of Standard Versus Energy-Dense Formulae on Gastric Retention, Caloric Delivery, and Glycaemia in Critically Ill Patients.. JPEN J Parenter Enteral Nutr, 45(4), 710-719. doi:10.1002/jpen.2065
  11. Horowitz, M., Wu, T., Rayner, C. K., Marathe, C. S., & Jones, K. L. (2021). Spontaneous or deliberate: effects of acute variations in glycemia on gastric emptying in type 1 diabetes. Diabetes Care, 44(2), 316-318. doi:10.2337/dci20-0067
  12. Xie, C., Huang, W., Young, R. L., Jones, K. L., Horowitz, M., Rayner, C. K., & Wu, T. (2021). Role of bile acids in the regulation of food intake, and their dysregulation in metabolic disease. Nutrients, 13(4), 1-16. doi:10.3390/nu13041104
  13. Horowitz, M., Rayner, C. K., Marathe, C. S., Wu, T., Umapathysivam, M., & Jones, K. L. (2021). Response to Dahl et al: Oral semaglutide improves postprandial glucose and lipid metabolism, and delays gastric emptying, in subjects with type 2 diabetes. Diabetes, Obesity and Metabolism, 23(10), 2411-2413. doi:10.1111/dom.14473
  14. Kamruzzaman, M., Horowitz, M., Jones, K. L., & Marathe, C. S. (2021). Gut-Based Strategies to Reduce Postprandial Glycaemia in Type 2 Diabetes. Frontiers in Endocrinology, 12, 1-10. doi:10.3389/fendo.2021.661877
  15. Malbert, C. -H., Chauvin, A., Horowitz, M., & Jones, K. L. (2021). Glucose-Sensing Mediated by Portal GLP-1 Receptor is Markedly Impaired in Insulin-Resistant Obese Animals.. Diabetes, 70(1), 99-110. doi:10.2337/db20-0361
  16. Xie, C., Huang, W., Wang, X., Trahair, L. G., Pham, H. T., Marathe, C. S., . . . Wu, T. (2021). Gastric emptying in health and type 2 diabetes: an evaluation using a 75g oral glucose drink. Diabetes Research and Clinical Practice, 171, 1-8. doi:10.1016/j.diabres.2020.108610
  17. Rayner, C. K., Watson, L. E., Phillips, L. K., Lange, K., Bound, M. J., Grivell, J., . . . Natali, A. (2021). Erratum to: Effects of sustained treatment with lixisenatide on gastric emptying and postprandial glucose metabolism in type 2 diabetes: A randomized controlled trial (Diabetes Care 2020, 43, 1813-1821). Diabetes Care, 44(1), 297. doi:10.2337/dc21-er01
  18. Hajishafiee, M., Elovaris, R. A., Jones, K. L., Heilbronn, L. K., Horowitz, M., Poppitt, S. D., & Feinle-Bisset, C. (2021). Effects of intragastric administration of L-tryptophan on the glycaemic response to a nutrient drink in men with type 2 diabetes - impacts on gastric emptying, glucoregulatory hormones and glucose absorption. Nutrition and Diabetes, 11(1), 3. doi:10.1038/s41387-020-00146-9
  19. Giezenaar, C., Oberoi, A., Jones, K. L., Horowitz, M., Chapman, I., & Soenen, S. (2021). Effects of age on blood pressure and heart rate responses to whey protein in younger and older men.. J Am Geriatr Soc, 69(5), 1291-1299. doi:10.1111/jgs.17083
  20. Jalleh, R. J., Marathe, C. S., Jones, K. L., Horowitz, M., & Rayner, C. K. (2021). Digesting the pathogenesis of diabetic gastroparesis. Journal of Diabetes and its Complications, 35(10), 3 pages. doi:10.1016/j.jdiacomp.2021.107992
  21. Chapman, M. J., Jones, K. L., Almansa, C., Barnes, C. N., Nguyen, D., & Deane, A. M. (2021). Blinded, Double-Dummy, Parallel-Group, Phase 2a Randomized Clinical Trial to Evaluate the Efficacy and Safety of a Highly Selective 5-Hydroxytryptamine Type 4 Receptor Agonist in Critically Ill Patients With Enteral Feeding Intolerance. JPEN. Journal of parenteral and enteral nutrition, 45(1), 115-124. doi:10.1002/jpen.1732
  22. Murthy, T. A., Grivell, J., Hatzinikolas, S., Chapple, L. -A. S., Chapman, M. J., Stevens, J. E., . . . Marathe, C. S. (2021). Acceleration of gastric emptying by insulin-induced hypoglycemia is dependent on the degree of hypoglycemia. The Journal of Clinical Endocrinology and Metabolism, 106(2), 364-371. doi:10.1210/clinem/dgaa854
  23. Jones, K. L., Morley, J. E., & Horowitz, M. (2020). Fall Prevention in Community-Dwelling Older Adults.. N Engl J Med, 382(26), 2580-2581. doi:10.1056/NEJMc2005662
  24. Giezenaar, C., Lange, K., Hausken, T., Jones, K. L., Horowitz, M., Chapman, I., & Soenen, S. (2020). Effects of Age on Acute Appetite-Related Responses to Whey-Protein Drinks, Including Energy Intake, Gastric Emptying, Blood Glucose, and Plasma Gut Hormone Concentrations-A Randomized Controlled Trial.. Nutrients, 12(4), 15 pages. doi:10.3390/nu12041008
  25. Sansome, D. J., Jones, K. L., Horowitz, M., Rayner, C. K., & Wu, T. (2020). Statins and glycaemic control in type 2 diabetes: Are bile acids relevant?. British Journal of Clinical Pharmacology, 86(12), 2 pages. doi:10.1111/bcp.14274
  26. Ali Abdelhamid, Y., Weinel, L. M., Hatzinikolas, S., Summers, M., Nguyen, T. A. N., Kar, P., . . . Jones, K. L. (2020). Autonomic function, postprandial hypotension and falls in older adults at one year after critical illness.. Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 22(1), 53-62. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/32102643
  27. Oberoi, A., Giezenaar, C., Clames, A., Bøhler, K., Lange, K., Horowitz, M., . . . Soenen, S. (2020). Whey protein drink ingestion before breakfast suppressed energy intake at breakfast and lunch, but not during dinner, and was less suppressed in healthy older than younger men. Nutrients, 12(11), 1-15. doi:10.3390/nu12113318
  28. Marathe, C. S., Pham, H., Marathe, J. A., Trahair, L. G., Huynh, L., Wu, T., . . . Jones, K. L. (2020). The relationship between plasma GIP and GLP-1 levels in individuals with normal and impaired glucose tolerance.. Acta Diabetol, 57(5), 583-587. doi:10.1007/s00592-019-01461-z
  29. Wu, T., Rayner, C. K., Jones, K. L., Xie, C., Marathe, C., & Horowitz, M. (2020). Role of intestinal glucose absorption in glucose tolerance. Current Opinion in Pharmacology, 55, 116-124. doi:10.1016/j.coph.2020.10.017
  30. Xie, C., Wang, X., Jones, K. L., Horowitz, M., Sun, Z., Little, T. J., . . . Wu, T. (2020). Role of endogenous glucagon-like peptide-1 enhanced by vildagliptin in the glycaemic and energy expenditure responses to intraduodenal fat infusion in type 2 diabetes. Diabetes, obesity & metabolism, 22(3), 383-392. doi:10.1111/dom.13906
  31. Malbert, C. -H., Chauvin, A., Horowitz, M., & Jones, K. L. (2020). Pancreatic GLP-1r binding potential is reduced in insulin-resistant pigs.. BMJ open diabetes research & care, 8(2), 9 pages. doi:10.1136/bmjdrc-2020-001540
  32. Pham, H., Phillips, L., Trahair, L., Hatzinikolas, S., Horowitz, M., & Jones, K. L. (2020). Longitudinal changes in the blood pressure responses to, and gastric emptying of, an oral glucose load in healthy older subjects. The journals of gerontology. Series A, Biological sciences and medical sciences, 75(2), 244-248. doi:10.1093/gerona/glz014
  33. Horowitz, M., Rayner, C. K., Marathe, C. S., Wu, T., & Jones, K. L. (2020). Glucagon- peptide-receptor agonists and the appropriate measurement of gastric emptying. Diabetes, Obesity and Metabolism, 22(12), 2504-2506. doi:10.1111/dom.14166
  34. Borg, M. J., Rayner, C. K., Jones, K. L., Horowitz, M., Xie, C., & Wu, T. (2020). Gastrointestinal mechanisms underlying the cardiovascular effect of metformin. Pharmaceuticals, 13(11), 1-14. doi:10.3390/ph13110410
  35. Marathe, C. S., Jones, K. L., Wu, T., Rayner, C. K., & Horowitz, M. (2020). Gastrointestinal autonomic neuropathy in diabetes. Autonomic Neuroscience: Basic and Clinical, 229, 1-9. doi:10.1016/j.autneu.2020.102718
  36. Jones, K. L., Huynh, L. Q., Hatzinikolas, S., Rigda, R. S., Phillips, L. K., Pham, H. T., . . . Horowitz, M. (2020). Exenatide once weekly slows gastric emptying of solids and liquids in healthy, overweight, subjects under steady-state concentrations. Diabetes, Obesity and Metabolism, 22(5), 788-797. doi:10.1111/dom.13956
  37. Xie, C., Jones, K. L., Rayner, C. K., & Wu, T. (2020). Enteroendocrine hormone secretion and metabolic control: importance of the region of the gut stimulation. Pharmaceutics, 12(9), 1-23. doi:10.3390/pharmaceutics12090790
  38. Rayner, C. K., Watson, L. E., Phillips, L. K., Lange, K., Bound, M. J., Grivell, J., . . . Natali, A. (2020). Effects of Sustained Treatment With Lixisenatide on Gastric Emptying and Postprandial Glucose Metabolism in Type 2 Diabetes: A Randomized Controlled Trial.. Diabetes Care, 43(8), 1813-1821. doi:10.2337/dc20-0190
  39. Stevens, J., Buttfield, M., Wu, T., Hatzinikolas, S., Pham, H., Lange, K., . . . Jones, K. (2020). Effects of sitagliptin on gastric emptying of, and the glycaemic and blood pressure responses to, a carbohydrate meal in type 2 diabetes. Diabetes, Obesity and Metabolism, 22(1), 51-58. doi:10.1111/dom.13864
  40. Zhang, X., Jones, K. L., Horowitz, M., Rayner, C. K., & Wu, T. (2020). Effects of proximal and distal enteral glucose infusion on cardiovascular response in health and type 2 diabetes. Journal of Clinical Endocrinology and Metabolism, 105(8), 2877-2884. doi:10.1210/clinem/dgaa341
  41. Wang, X., Xie, C., Marathe, C. S., Malbert, C. -H., Horowitz, M., Jones, K. L., . . . Wu, T. (2020). Disparities in gastric emptying and postprandial glycaemia between Han Chinese and Caucasians with type 2 diabetes.. Diabetes research and clinical practice, 159, 107951. doi:10.1016/j.diabres.2019.107951
  42. Huang, W., Xie, C., Young, R. L., Zhao, J., Ebendorff-Heidepriem, H., Jones, K. L., . . . Wu, T. (2020). Development of innovative tools for investigation of nutrient-gut interaction. World Journal of Gastroenterology, 26(25), 3562-3576. doi:10.3748/wjg.v26.i25.3562
  43. Xie, C., Wang, X., Jones, K. L., Horowitz, M., Sun, Z., Little, T. J., . . . Wu, T. (2020). Comparative effects of intraduodenal glucose and fat infusion on blood pressure and heart rate in type 2 diabetes. Frontiers in Nutrition, 7, 1-6. doi:10.3389/fnut.2020.582314
  44. Oberoi, A., Giezenaar, C., Jensen, C., Lange, K., Hausken, T., Jones, K. L., . . . Soenen, S. (2020). Acute effects of whey protein on energy intake, appetite and gastric emptying in younger and older, obese men. Nutrition and Diabetes, 10(1), 37-1-37-9. doi:10.1038/s41387-020-00139-8
  45. Jalleh, R., Pham, H., Marathe, C. S., Wu, T., Buttfield, M. D., Hatzinikolas, S., . . . Jones, K. L. (2020). Acute Effects of Lixisenatide on Energy Intake in Healthy Subjects and Patients with Type 2 Diabetes: Relationship to Gastric Emptying and Intragastric Distribution.. Nutrients, 12(7), 1-8. doi:10.3390/nu12071962
  46. Riceman, M. D., Bound, M., Grivell, J., Hatzinikolas, S., Piotto, S., Nguyen, N. Q., . . . Phillips, L. K. (2019). The prevalence and impact of low faecal elastase-1 in community-based patients with type 2 diabetes. Diabetes Research and Clinical Practice, 156, 107822. doi:10.1016/j.diabres.2019.107822
  47. Pham, H., Trahair, L., Phillips, L., Rayner, C., Horowitz, M., & Jones, K. (2019). A randomized, crossover study of the acute effects of acarbose and gastric distension, alone and combined, on postprandial blood pressure in healthy older adults. BMC Geriatrics, 19(1), 241. doi:10.1186/s12877-019-1251-7
  48. Pham, H., Marathe, C. S., Phillips, L. K., Trahair, L. G., Hatzinikolas, S., Huynh, L., . . . Jones, K. L. (2019). Longitudinal changes in fasting and glucose-stimulated GLP-1 and GIP in healthy older subjects.. The Journal of clinical endocrinology and metabolism, 1054(12), 6201-6206. doi:10.1210/jc.2019-01262
  49. Pham, H., Phillips, L., Marathe, C. S., Trahair, L., Hatzinikolas, S., Huynh, L. Q., . . . Jones, K. (2019). Longitudinal changes in fasting and glucose-stimulated GIP and GLP-1 in healthy older subjects. Diabetologia, 62, S128-S129.

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  50. Borg, M. J., Jones, K. L., Sun, Z., Horowitz, M., Rayner, C. K., & Wu, T. (2019). Metformin attenuates the postprandial fall in blood pressure in type 2 diabetes. Diabetes, Obesity and Metabolism, 21(5), 1251-1254. doi:10.1111/dom.13632
  51. Watson, L., Phillips, L., Wu, T., Bound, M., Checklin, H., Grivell, J., . . . Rayner, C. (2019). Title: Differentiating the effects of whey protein and guar gum preloads on postprandial glycemia in type 2 diabetes. Clinical Nutrition, 38(6), 2827-2832. doi:10.1016/j.clnu.2018.12.014
  52. Pham, H., Holen, I. S., Phillips, L. K., Hatzinikolas, S., Huynh, L. Q., Wu, T., . . . Jones, K. L. (2019). The Effects of a Whey Protein and Guar Gum-Containing Preload on Gastric Emptying, Glycaemia, Small Intestinal Absorption and Blood Pressure in Healthy Older Subjects.. Nutrients, 11(11), 13 pages. doi:10.3390/nu11112666
  53. Watson, L. E., Phillips, L. K., Wu, T., Bound, M. J., Jones, K. L., Horowitz, M., & Rayner, C. K. (2019). Longitudinal evaluation of gastric emptying in type 2 diabetes. Diabetes Research and Clinical Practice, 154, 27-34. doi:10.1016/j.diabres.2019.06.010
  54. Rayner, C. K., Jones, K., & Horowitz, M. (2019). Is making the stomach pump better the answer to gastroparesis?. Gastroenterology, 156(6), 1555-1557. doi:10.1053/j.gastro.2019.03.030
  55. Bitarafan, V., Fitzgerald, P. C., Little, T. J., Meyerhof, W., Jones, K. L., Wu, T., . . . Feinle-Bisset, C. (2019). Intragastric administration of the bitter tastant, quinine, lowers the glycemic response to a nutrient drink without slowing gastric emptying, in healthy men.. American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 318(2), R263-R273. doi:10.1152/ajpregu.00294.2019
  56. Kar, P., Plummer, M., Ali Abdelhamid, Y., Giersch, E. J., Summers, M. J., Weinel, L. M., . . . Deane, A. M. (2019). Incident diabetes in survivors of critical illness and mechanisms underlying persistent glucose intolerance: a prospective cohort study. Critical Care Medicine, 47(2), 103-111. doi:10.1097/CCM.0000000000003524
  57. Marathe, C. S., Marathe, J. A., Rayner, C. K., Kar, P., Jones, K. L., & Horowitz, M. (2019). Hypoglycaemia and gastric emptying. Diabetes, Obesity and Metabolism, 21(3), 491-498. doi:10.1111/dom.13570
  58. Watson, L. E., Xie, C., Wang, X., Li, Z., Phillips, L. K., Sun, Z., . . . Wu, T. (2019). Gastric emptying in patients with well-controlled type 2 diabetes compared with young and older control subjects without diabetes. Journal of Clinical Endocrinology and Metabolism, 104(8), 3311-3319. doi:10.1210/jc.2018-02736
  59. Jones, K. L., Rigda, R. S., Buttfield, M. D. M., Hatzinikolas, S., Pham, H. T., Marathe, C. S., . . . Horowitz, M. (2019). Effects of lixisenatide on postprandial blood pressure, gastric emptying and glycaemia in healthy people and people with type 2 diabetes. Diabetes, Obesity and Metabolism, 21(5), 1158-1167. doi:10.1111/dom.13633
  60. Jalleh, R., Marathe, C. S., Rayner, C. K., Jones, K. L., & Horowitz, M. (2019). Diabetic Gastroparesis and Glycaemic Control.. Curr Diab Rep, 19(12), 153. doi:10.1007/s11892-019-1281-8
  61. Zhang, X., Young, R. L., Bound, M., Hu, S., Jones, K. L., Horowitz, M., . . . Wu, T. (2019). Comparative effects of proximal and distal small intestinal glucose exposure on glycemia, incretin hormone secretion, and the incretin effect in health and type 2 diabetes. Diabetes Care, 42(4), 520-528. doi:10.2337/dc18-2156
  62. Borg, M. J., Bound, M., Grivell, J., Sun, Z., Jones, K. L., Horowitz, M., . . . Wu, T. (2019). Comparative effects of proximal and distal small intestinal administration of metformin on plasma glucose and glucagon-like peptide-1, and gastric emptying after oral glucose, in type 2 diabetes. Diabetes, Obesity and Metabolism, 21(3), 640-647. doi:10.1111/dom.13567
  63. Pham, H., Phillips, L. K., & Jones, K. L. (2019). Acute effects of nutritive and non-nutritive sweeteners on postprandial blood pressure. Nutrients, 11(8), 1-21. doi:10.3390/nu11081717
  64. Watson, L. E., Phillips, L., Wu, T., Bound, M., Checklin, H. L., Grivell, J., . . . Rayner, C. (2019). A whey/guar "preload" improves postprandial glycaemia and glycated haemoglobin levels in type 2 diabetes: a 12-week, single-blind, randomized, placebo-controlled trial. Diabetes, Obesity and Metabolism, 21(4), 930-938. doi:10.1111/dom.13604
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  66. Wu, T., Rayner, C. K., Marathe, C. S., Jones, K. L., & Horowitz, M. (2018). Glucagon receptor signalling-backwards and forwards. Expert Opinion on Investigational Drugs, 27(2), 135-138. doi:10.1080/13543784.2018.1428306
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  234. Horowitz, M., Feinle-Bisset, C., Jones, K., & Nauck, M. (2004). Orlistat augments postprandial increases in glucagon-like peptide-1 in obese type 2 diabetic patients - Response to Damci et al.. Diabetes Care, 27(11), 2770. doi:10.2337/diacare.27.11.2770
  235. Sturm, K., Parker, B., Wishart, J., Feinle-Bisset, C., Jones, K., Chapman, I., & Horowitz, M. (2004). Energy intake and appetite are related to antral area in healthy young and older subjects. American Journal of Clinical Nutrition, 80(3), 656-667. doi:10.1093/ajcn/80.3.656
  236. O'Donovan, D., Horowitz, M., Russo, A., Feinle-Bisset, C., Murolo, N., Gentilcore, D., . . . Jones, K. (2004). Effects of lipase inhibition on gastric emptying of, and on the glycaemic, insulin and cardiovascular responses to, a high-fat/carbohydrate meal in type 2 diabetes. Diabetologia, 47(12), 2208-2214. doi:10.1007/s00125-004-1591-4
  237. O'Donovan, D., Doran, S., Feinle-Bisset, C., Jones, K., Meyer, J., Wishart, J., . . . Horowitz, M. (2004). Effect of variations in small intestinal glucose delivery on plasma glucose, insulin, and incretin hormones in healthy subjects and type 2 diabetes. Journal of Clinical Endocrinology and Metabolism, 89(7), 3431-3435. doi:10.1210/jc.2004-0334
  238. Russo, A., Stevens, J., Giles, N., Krause, G., O'Donovan, D., Horowitz, M., & Jones, K. (2004). Effect of the motilin agonist KC 11458 on gastric emptying in diabetic gastroparesis. Alimentary Pharmacology & Therapeutics, 20(3), 333-338. doi:10.1111/j.1365-2036.2004.02066.x
  239. Gentilcore, D., O'Donovan, D., Jones, K., & Horowitz, M. (2003). Nutrition therapy for diabetic gastroparesis. Current Diabetes Reports, 3(5), 418-426. doi:10.1007/s11892-003-0087-9
  240. O'Donovan, D., Feinle-Bisset, C., Jones, K., & Horowitz, M. (2003). Idiopathic and diabetic gastroparesis. Current Treatment Options in Gastroenterology, 6(4), 299-309. doi:10.1007/s11938-003-0022-9
  241. Russo, A., Stevens, J., Wilson, T., Wells, F., Tonkin, A., Horowitz, M., & Jones, K. (2003). Guar attenuates fall in postprandial blood pressure and slows gastric emptying of oral glucose in type 2 diabetes. Digestive Diseases and Sciences, 48(7), 1221-1229. doi:10.1023/A:1024182403984
  242. Berry, M., Russo, A., Wishart, J., Tonkin, A., Horowitz, M., & Jones, K. (2003). Effect of solid meal on gastric emptying of, and glycemic and cardiovascular responses to, liquid glucose in older subjects. American Journal of Physiology-Gastrointestinal and Liver Physiology, 284(4), G655-G662. doi:10.1152/ajpgi.00163.2002
  243. Pilichiewicz, A., O'Donovan, D., Feinle-Bisset, C., Lei, Y., Wishart, J., Bryant, L., . . . Jones, K. (2003). Effect of lipase inhibition on gastric emptying of, and the glycemic and incretin responses to, an oil/aqueous drink in type 2 diabetes mellitus. Journal of Clinical Endocrinology and Metabolism, 88(8), 3829-3834. doi:10.1210/jc.2003-030199
  244. Horowitz, M., Jones, K., Harding, P., & Wishart, J. (2002). Relationship between the effects of cisapride on gastric emptying and plasma glucose concentrations in diabetic gastroparesis. Digestion, 65(1), 41-46. doi:10.1159/000051930
  245. O'Donovan, D., Feinle-Bisset, C., Tonkin, A., Horowitz, M., & Jones, K. (2002). Postprandial hypotension in response to duodenal glucose delivery in healthy older subjects. Journal of Physiology-London, 540(2), 673-679. doi:10.1113/jphysiol.2001.013442
  246. Jones, K., Wishart, J., Berry, M., Russo, A., Xia, H., Talley, N., & Horowitz, M. (2002). Helicobacter pylori infection is not associated with delayed gastric emptying or upper gastrointestinal symptoms in diabetes mellitus. Digestive Diseases and Sciences, 47(4), 704-709. doi:10.1023/A:1014763210890
  247. Horowitz, M., O'Donovan, D., Jones, K., Feinle-Bisset, C., Rayner, C., & Samsom, M. (2002). Gastric emptying in diabetes: clinical significance and treatment. Diabetic Medicine, 19(3), 177-194. doi:10.1046/j.1464-5491.2002.00658.x
  248. Su, Y., Doran, S., Wittert, G., Chapman, I., Jones, K., Smout, A., & Horowitz, M. (2002). Effects of exogenous corticotropin-releasing factor on antropyloroduodenal motility and appetite in humans. American Journal of Gastroenterology, 97(1), 49-57. doi:10.1111/j.1572-0241.2002.05422.x
  249. Jones, K., Russo, A., Berry, M., Stevens, J., Wishart, J., & Horowitz, M. (2002). A longitudinal study of gastric emptying and upper gastrointestinal symptoms in patients with diabetes mellitus. American Journal of Medicine, 113(6), 449-455. doi:10.1016/S0002-9343(02)01228-7
  250. O'Donovan, D. G., Jones, K. L., Feinle, C., Tonkin, A., & Horowitz, M. (2001). Effect of variations in duodenal glucose delivery on blood pressure in healthy older subjects.. GASTROENTEROLOGY, 120(5), A267-A268. doi:10.1016/S0016-5085(08)81326-1
  251. Rayner, C., Samsom, M., Jones, K., & Horowitz, M. (2001). Relationships of upper gastrointestinal motor and sensory function with glycemic control. Diabetes Care, 24(2), 371-381. doi:10.2337/diacare.24.2.371
  252. Jones, K., Russo, A., Stevens, J., Wishart, J., Berry, M., & Horowitz, M. (2001). Predictors of delayed gastric emptying in diabetes. Diabetes Care, 24(7), 1264-1269. doi:10.2337/diacare.24.7.1264
  253. Jones, K., MacIntosh, C., Su, Y., Wells, F., Chapman, I., Tonkin, A., & Horowitz, M. (2001). Guar gum reduces postprandial hypotension in older people. Journal of the American Geriatrics Society, 49(2), 162-167. doi:10.1046/j.1532-5415.2001.49037.x
  254. Horowitz, M., Su, Y., Rayner, C., & Jones, K. (2001). Gastroparesis: prevalence clinical significance and treatment. Canadian Journal of Gastroenterology, 15(12), 805-816. doi:10.1155/2001/628102
  255. Su, Y., Yandell, R., Doran, S., Leelakusolvong, S., Rayner, C., Chapman, I., . . . Horowitz, M. (2001). Effects of the nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester (L-NAME) on antropyloroduodenal motility and appetite in response to intraduodenal lipid infusion in humans. Scandinavian Journal of Gastroenterology, 36(9), 948-954. doi:10.1080/003655201750305468
  256. Beckoff, K., MacIntosh, C., Chapman, I., Wishart, J., Morris, H., Horowitz, M., & Jones, K. (2001). Effects of glucose supplementation on gastric emptying, blood glucose homeostasis, and appetite in the elderly. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 280(2), R570-R576. doi:10.1152/ajpregu.2001.280.2.r570
  257. Rayner, C. K., Su, Y. C., Doran, S. M., Jones, K. L., Malbert, C. H., & Horowitz, M. (2000). The stimulation of antral motility by erythromycin is attenuated by hyperglycemia. American Journal of Gastroenterology, 95(9), 2233-2241. doi:10.1111/j.1572-0241.2000.02250.x
  258. Jones, K. L., Wishart, J. M., Berry, M. K., Abitbol, J. L., & Horowitz, M. (2000). Effects of fedotozine on gastric emptying and upper gastrointestinal symptoms in diabetic gastroparesis. Alimentary Pharmacology and Therapeutics, 14(7), 937-943. doi:10.1046/j.1365-2036.2000.00790.x
  259. Sun, W., Doran, S., Jones, K., Davidson, G., Dent, J., & Horowitz, M. (2000). Long-term effects of pyloromyotomy on pyloric motility and gastric emptying in humans. American Journal of Gastroenterology, 95(1), 92-100. doi:10.1016/S0002-9270(99)00764-9
  260. Kwiatek, M. A., Jones, K. L., Burch, W. M., Horowitz, M., & Bartholomeusz, F. D. L. (1999). Use of Technegas as a radiopharmaceutical for the measurement of gastric emptying. European Journal of Nuclear Medicine, 26(8), 903-906. doi:10.1007/s002590050466
  261. Jones, K. L., & Kong, M. F. (1999). The effect of erythromycin on gastric emptying is modified by physiological changes in the blood glucose concentration. American Journal of Gastroenterology, 94(8), 2074-2079. doi:10.1111/j.1572-0241.1999.01280.x
  262. Kong, M. F., Horowitz, M., Jones, K. L., Wishart, J. M., & Harding, P. E. (1999). Natural history of diabetic gastroparesis. Diabetes Care, 22(3), 503-507. doi:10.2337/diacare.22.3.503
  263. Jones, K. L., Berry, M., Kong, M. F., Kwiatek, M. A., Samsom, M., & Horowitz, M. (1999). Hyperglycemia attenuates the gastrokinetic effect of erythromycin and affects the perception of postprandial hunger in normal subjects. Diabetes Care, 22(2), 339-344. doi:10.2337/diacare.22.2.339
  264. MacIntosh, C., Andrews, J., Jones, K., Wishart, J., Morris, H., Jansen, J., . . . Chapman, I. (1999). Effects of age on concentrations of plasma cholecystokinin, glucagon-like peptide 1, and peptide YY and their relation to appetite and pyloric motility. American Journal of Clinical Nutrition, 69(5), 999-1006. doi:10.1093/ajcn/69.5.999
  265. Wishart, J., Horowitz, M., Morris, H., Jones, K., & Nauck, M. (1998). Relation between gastric emptying of glucose and plasma concentrations of glucagon-like peptide-1. Peptides, 19(6), 1049-1053. doi:10.1016/S0196-9781(98)00052-7
  266. Jones, K., Tonkin, A., Horowitz, M., Wishart, J., Carney, B., Guha, S., & Green, L. (1998). Rate of gastric emptying is a determinant of postprandial hypotension in non insulin-dependent diabetes mellitus. Clinical Science, 94(1), 65-70. doi:10.1042/cs0940065
  267. Penagini, R., Hebbard, G., Horowitz, M., Dent, J., Bermingham, H., Jones, K., & Holloway, R. (1998). Motor function of the proximal stomach and visceral perception in gastro-oesophageal reflux disease. Gut, 42(2), 251-257. doi:10.1136/gut.42.2.251
  268. Horowitz, M., Rayner, C., Kong, M. F., Jones, K., Wishart, J., Sun, W. M., & Fraser, R. (1998). Gastrointestinal motor function in diabetes mellitus. Relationship to blood glucose concentrations. Journal of Gastroenterology and Hepatology, 13(SUPPL.1), S239S245. doi:10.1046/j.1440-1746.1998.01741.x
  269. Sun, W., Doran, S., Jones, K., Ooi, E., Boeckxstaens, G., Hebbard, G., . . . Horowitz, M. (1998). Effects of nitroglycerin on liquid gastric emptying and antropyloroduodenal motility. American Journal of Physiology: Gastrointestinal and Liver Physiology, 275(5), G1173-G1178. doi:10.1152/ajpgi.1998.275.5.g1173
  270. Doran, S., Jones, K., Andrews, J., & Horowitz, M. (1998). Effects of meal volume and posture on gastric emptying of solids and appetite. American Journal of Physiology. Regulatory Integrative and Comparative Physiology, 275(5), R1712-R1718. doi:10.1152/ajpregu.1998.275.5.r1712
  271. Jones, K. L., Horowitz, M., Berry, M., Wishart, J. M., & Guha, S. (1997). Blood glucose concentration influences postprandial fullness in IDDM. Diabetes Care, 20(7), 1141-1146. doi:10.2337/diacare.20.7.1141
  272. Jones, K., Tonkin, A., Horowitz, M., Wishart, J., Carney, B., Guha, S., & Green, L. (1997). The rate of gastric emptying is a significant determinant of postprandial hypotension in non-insulin dependent diabetes mellitus.. GASTROENTEROLOGY, 112(4), A756. Retrieved from http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997WV41903014&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1f051b2c0ced71d786748f61000f9895
  273. Cook, C., Andrews, J., Jones, K., Wittert, G., Chapman, I., Morley, J., & Horowitz, M. (1997). The effects of small intestinal nutrient infusion on appetite and pyloric motility are modified by age. American Journal of Physiology. Regulatory Integrative and Comparative Physiology, 273(2), R755-R761. doi:10.1152/ajpregu.1997.273.2.R755
  274. Wishart, J., Horowitz, M., Campbell, J., & Jones, K. (1997). The effect of cisapride on oral and intravenous glucose tolerance in normal subjects. Journal of Gastroenterology and Hepatology, 12(12), 795-800. doi:10.1111/j.1440-1746.1997.tb00374.x
  275. Sun, W., Hebbard, G., Malbert, C., Jones, K., Doran, S., Horowitz, M., & Dent, J. (1997). Spatial patterns of fasting and fed antropyloric pressure waves in humans.. Journal of Physiology, 503(Part 2), 455-462. doi:10.1111/j.1469-7793.1997.455bh.x
  276. Jones, K., Doran, S., Hveem, K., Bartholomeusz, F., Morley, J., Sun, W., . . . Horowitz, M. (1997). Relationship between postprandial satiation and antral area in normal subjects. American Journal of Clinical Nutrition, 66(1), 127-132. doi:10.1093/ajcn/66.1.127
  277. Horowitz, M., Fraser, R., Hebbard, G., Jones, K., Wishart, J., & Sun, W. M. (1997). Effects of diabetes mellitus on gastrointestinal motor function. Neuroscience Research Communications, 21(1), 75-82. doi:10.1002/%28SICI%291520-6769%28199707%2921:1%3C75::AID-NRC210%3E3.0.CO;2-L
  278. Hveem, K., Jones, K., Chatterton, B., & Horowitz, M. (1996). Scintigraphic measurement of gastric emptying and ultrasonographic assessment of antral area: Relation to appetite. Gut, 38(6), 816-821. doi:10.1136/gut.38.6.816
  279. Horowitz, M., Cunningham, K. M., Wishart, J. M., Jones, K. L., & Read, N. W. (1996). The effect of short-term dietary supplementation with glucose on gastric emptying of glucose and fructose and oral glucose tolerance in normal subjects. Diabetologia, 39(4), 481-486. doi:10.1007/s001250050469
  280. Horowitz, M., Cunningham, K., Wishart, J., Jones, K., & Read, N. (1996). The effect of short-term dietary supplementation with glucose on gastric emptying of glucose and fructose and oral glucose tolerance in normal subjects.. Diabetologia, 39(4), 481-486. doi:10.1007/BF00400681
  281. Horowitz, M., Wishart, J., Jones, K., & Hebbard, G. (1996). Gastric emptying in diabetes: an overview. Diabetic Medicine, 13(9 Suppl 5), S16-S22. doi:10.999/1234
  282. Jones, K., Horowitz, M., Carney, B., Wishart, J., Guha, S., & Green, L. (1996). Gastric emptying in "early" non-insulin dependent diabetes mellitus. Journal of Nuclear Medicine, 37(10), 1643-1648. Retrieved from http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1996VL58100023&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1f051b2c0ced71d786748f61000f9895
  283. Jones, K. L., Horowitz, M., Carney, B. I., Sun, W. M., & Chatterton, B. E. (1996). Effects of cisapride on gastric emptying of oil and aqueous meal components, hunger, and fullness.. Gut, 38(3), 310-315.
  284. Jones, K., Horowitz, M., Wishart, J., Maddox, A., Harding, P., & Chatterton, B. (1995). Relationships between gastric emptying, intragastric meal distribution and blood glucose concentrations in diabetes mellitus. Journal of Nuclear Medicine, 36(12), 2220-2228. Retrieved from http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1995TK40900019&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1f051b2c0ced71d786748f61000f9895
  285. Sun, W., Smout, A., Malbert, C., Edelbroek, M., Jones, K., Dent, J., & Horowitz, M. (1995). Relationship between surface electrogastrography and antropyloric pressures. American Journal of Physiology. Gastrointestinal and Liver Physiology, 268(3), G424-G430. doi:10.1152/ajpgi.1995.268.3.g424
  286. Wishart, J., Horowitz, M., Morris, H., Need, A., Russo, A., Jones, K., . . . Nordin, B. (1995). Relationship between fractional calcium absorption and gastric emptying. European Journal of Clinical Investigation, 25(2), 123-127. doi:10.1111/j.1365-2362.1995.tb01536.x
  287. Carney, B., Jones, K., Horowitz, M., Sun, W., Penagini, R., & Meyer, J. (1995). Gastric emptying of oil and aqueous meal components in pancreatic insufficiency: effect of posture and on appetite. American Journal of Physiology. Gastrointestinal and Liver Physiology, 268(6), G925-G932. doi:10.1152/ajpgi.1995.268.6.g925
  288. Jones, K., Edelbroek, M., Horowitz, M., Sun, W., Dent, J., Roelofs, J., . . . Akkermans, L. (1995). Evaluation of antral motility in humans using manometry and scintigraphy. Gut, 37(5), 643-648. doi:10.1136/gut.37.5.643
  289. Sun, W., Penagini, R., Hebbard, G., Malbert, C., Jones, K., Emery, S., . . . Horowitz, M. (1995). Effect of drink temperature on antropyloroduodenal motility and gastric electrical activity in humans. Gut, 37(3), 329-334. doi:10.1136/gut.37.3.329
  290. Carney, B. I., Jones, K. L., Horowitz, M., Sun, W. M., Hebbard G., & Edelbroek, M. A. L. (1994). Stereospecific effects of tryptophan on gastric emptying and hunger in humans. Journal of Gastroenterology and Hepatology, 9(6), 557-563. doi:10.1111/j.1440-1746.1994.tb01560.x
  291. Horowitz, M., Jones, K., Edelbroek, M. A. L., Smout, A. J. P. M., & Read, N. W. (1993). The effect of posture on gastric emptying and intragastric distribution of oil and aqueous meal components and appetite. Gastroenterology, 105(2), 382-390. doi:10.1016/0016-5085(93)90711-K

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