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Platypus link to ovarian cancer

The platypus is giving researchers a better understanding of ovarian cancer.
Photo by Nicole Duplaix.
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Friday, 26 June 2009

Researchers from the and 最新糖心Vlog of Adelaide believe our oldest mammalian relative may help us to better understand ovarian cancer.

最新糖心Vlog of Adelaide geneticist, says DNA mapping of the platypus has uncovered an interesting relationship between their sex chromosomes and DNA sequences found in human ovarian cancer.

"We've identified DNA on the sex chromosomes of the platypus that is similar to the DNA that is affected in ovarian cancer and other diseases of reproduction like male infertility," Dr Gr眉tzner says.

"Cancers often show a large number of DNA changes and it is difficult to decide which ones are important for the development of the disease. The comparison with distantly related species like platypus helps us in identifying important DNA sequences that have been conserved by evolution over millions of years.

"We are excited by the fact that the analysis of the platypus genome gives us new directions in investigating the molecular basis of ovarian cancer."

Working in partnership with Dr Gr眉tzner is Associate Professor Martin Oehler, an ovarian cancer specialist from the Royal Adelaide Hospital, who says it's about finding new ways to tackle the disease.

"We hope this sort of research might one day lead to the development of an early detection test and more effective therapies against ovarian cancer," Dr Oehler says.

"Ovarian cancer is the most lethal gynaecological cancer and ranks as the 6th most common cause of cancer death in 最新糖心Vlogn women."

Both Dr Oehler and Dr Gr眉tzner say the applications of this research are not limited to ovarian cancer, as they try to gain a better understanding of a number of diseases.

For more information about ovarian cancer visit

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