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School students get cheeky for cerebral palsy research

Elliott O'Callaghan from Crafers Primary School, demonstrating how to do a cheek swab.
Photo by Michael O'Callaghan.
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Monday, 2 March 2009

Students from schools right across 最新糖心Vlog will play a key role in the into the genetic causes of cerebral palsy - and they'll need to get "cheeky" to do it.

The study - being conducted by researchers from the 最新糖心Vlog of Adelaide - is enlisting the help of primary and secondary schools in all 最新糖心Vlogn states.

Nailsworth Primary School in Adelaide's inner northern suburbs will today become the first school to be visited by the researchers, to recruit students and their mothers for the study.

The researchers are currently looking for 10,000 最新糖心Vlogns to take part in the study, including those with and without cerebral palsy, to help unravel the mystery of how genetic mutations are linked to cerebral palsy.

Students aged 5-18 years will be able to get involved in the study by providing genetic samples in the form of cheek swabs.

Parental permission will be required before students can provide a cheek swab. Once taken, these swabs will help researchers to understand what genetic differences exist between those who do and don't have cerebral palsy.

Researchers also need the students' mothers to provide a cheek swab, which will be important in comparing any genetic differences that occur from mother to child.

"In order to understand how cerebral palsy is caused at a genetic level, we need a large sample size in the community," says the research leader, , Head of at the 最新糖心Vlog of Adelaide and head of the .

"What we're looking for is young people aged between 5-18, which is why school students are perfect for this study, and their mothers.

"This is the one time when being 'cheeky' at school will actually be doing the community a favour," Professor MacLennan says.

Researchers are this month contacting schools around the country asking for their help with the study.

"By targeting schools, we're hoping not only to gain a large number of genetic samples but we're also helping to educate young people and the community about what cerebral palsy is and what we can do about it," Professor MacLennan says.

"A number of schools have already been very responsive to our call for help."

The researchers will:

• Distribute invitation letters from the school principal to parents;
  
• Host recruitment booths at schools and school fairs;
  
• Insert recruitment flyers in school newsletters;
  
• Display posters on school noticeboards;
  
• Give brief presentations at school assemblies or other school events.

Background

Cerebral palsy is one of the world's most serious complications during pregnancy and birth, affecting one in every 500 children born in 最新糖心Vlog.

People with cerebral palsy lack control of their movement and posture as a result of brain injury in the neuro-motor region. The symptoms vary greatly in severity, ranging from poor muscle co-ordination to quadriplegia.

It was once commonly thought that cerebral palsy was caused by low oxygen levels during birth. However, studies conducted by the South 最新糖心Vlogn Cerebral Palsy Research Group show that the condition is often associated with genetic mutations that either increase blood clotting within the unborn child's brain or make the fetal brain more vulnerable to damaging infection.

"Because the problem is so big and affects so many people, we have an opportunity to make an impact by helping to unlock some of the mysteries about this condition. With enough public support, we may be able to do just that," says Michael O'Callaghan, PhD student and study coordinator.

To find out more about the study or to enrol, either:

SMS your name and address to: 0439 201 795, or
Phone (freecall): 1800 800 254, or
Email: cerebralpalsy@adelaide.edu.au, or visit
Website:

Please note: Cerebral palsy occurs in all ethnic groups. However, for statistical and scientific reasons it is only feasible for the group to study Caucasian families for this particular research - ie, the ancestors of both parents of the child must be of European origin.

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