最新糖心Vlog

BIOINF 7160 - Transcriptomics Applications

North Terrace Campus - Semester 1 - 2022

This course teaches the underlying theory and skills for design and analysis of transcriptome sequencing/assembly experiments and datasets. This will include differential gene expression and transcript assembly. Theoretical background will cover relevant computational, statistical, and network theory, as well as the key biological processes which are under investigation. Practical analysis will involve use of relevant assembly/expression analysis software, R Studio and Bash scripting and/or a compiled programming language in the context of an HPC environment.

  • General Course Information
    Course Details
    Course Code BIOINF 7160
    Course Transcriptomics Applications
    Coordinating Unit School of Biological Sciences
    Term Semester 1
    Level Postgraduate Coursework
    Location/s North Terrace Campus
    Units 3
    Contact 12 x 1 hour lectures, 12 x 4 hour practicals
    Available for Study Abroad and Exchange Y
    Restrictions Available to Graduate Certificate in Bioinformatics, Graduate Diploma in Bioinformatics and Master of Bioinformatics
    Assessment Practical tasks and project submission
    Course Staff

    Course Coordinator: Professor David Adelson

    Course Timetable

    The full timetable of all activities for this course can be accessed from .

  • Learning Outcomes
    Course Learning Outcomes
    1. Use modern literate programming tools such as R Studio Notebooks.
    2. Analyse a biological question in order to develop a research analysis pipeline.
    3. Use a variety of publicly available data resources and software tools to perform transcriptomic analyses.
    4. Implement approaches to ensure reproducibility of a research analysis.
    5. Use and communicate statistical concepts to establish and communicate the reliability of transcriptomic analyses.
    6. Employ effective techniques to communicate complex research results to a non-specialist audience.
    7. Produce a comprehensive analytical report on a transcriptomics research problem.
    最新糖心Vlog Graduate Attributes

    This course will provide students with an opportunity to develop the Graduate Attribute(s) specified below:

    最新糖心Vlog Graduate Attribute Course Learning Outcome(s)

    Attribute 1: Deep discipline knowledge and intellectual breadth

    Graduates have comprehensive knowledge and understanding of their subject area, the ability to engage with different traditions of thought, and the ability to apply their knowledge in practice including in multi-disciplinary or multi-professional contexts.

    1, 2, 3, 4, 5, 6, 7

    Attribute 2: Creative and critical thinking, and problem solving

    Graduates are effective problems-solvers, able to apply critical, creative and evidence-based thinking to conceive innovative responses to future challenges.

    2, 4, 5, 6, 7

    Attribute 3: Teamwork and communication skills

    Graduates convey ideas and information effectively to a range of audiences for a variety of purposes and contribute in a positive and collaborative manner to achieving common goals.

    1, 5, 6, 7

    Attribute 4: Professionalism and leadership readiness

    Graduates engage in professional behaviour and have the potential to be entrepreneurial and take leadership roles in their chosen occupations or careers and communities.

    1, 2, 3, 4, 5, 6, 7

    Attribute 5: Intercultural and ethical competency

    Graduates are responsible and effective global citizens whose personal values and practices are consistent with their roles as responsible members of society.

    5, 6, 7

    Attribute 7: Digital capabilities

    Graduates are well prepared for living, learning and working in a digital society.

    1, 2, 3, 4, 5, 6, 7
  • Learning & Teaching Activities
    Learning & Teaching Modes
    Practicals are supported by lectures that build students student’s understanding of the details of performing complete transcriptomics analysis pipelines. An integrative project and associated report preparation will help develop students’ capacity to perform complex transcriptomics analyses and communicate analytical results to others in an effective way.
    Workload

    The information below is provided as a guide to assist students in engaging appropriately with the course requirements.

    A student enrolled in a 3 unit course, such as this, should expect to spend, on average 12 hours per week on the studies required. This includes both the formal contact time required to the course (e.g., lectures and practicals), as well as non-contact time (e.g., reading and revision).

    Learning Activities Summary
    The course covers practical aspects of conducting transcriptomics research analyses using contemporary tools such as the R statistical environment using R Studio, literate programming using R markdown notebooks and presenting analyses to clients and other researchers.

    The course will involve a scaffolded development of techniques used to perform bioinformatics and statistical analyses of small transcriptomics datasets with supporting lectures to establish an understanding of the background theory for the practical studies.

    The development of analysis techniques will culminate with a single large project that will make use of the techniques developed previously in the course. This project will require that students submit a preliminary analysis report and a full report explaining the results of the analysis at the level of executive summary, complete analytical approach and in depth biological interpretation.
  • Assessment

    The 最新糖心Vlog's policy on Assessment for Coursework Programs is based on the following four principles:

    1. Assessment must encourage and reinforce learning.
    2. Assessment must enable robust and fair judgements about student performance.
    3. Assessment practices must be fair and equitable to students and give them the opportunity to demonstrate what they have learned.
    4. Assessment must maintain academic standards.

    Assessment Summary
    Assessment task Type of assessment Percentage of total assessment Hurdle Outcomes being assessed Timing of assessment
    Practical tasks Formative and summative 60 No Weeks 2-7
    Final project progress Formative and summative 10 No Week 9
    Final project submission Summative 30 No Week 12
    Assessment Detail
    Practical tasks (6x: total of 60%)
    Each practical will include an assessment tasks which will be dependent on the aspects of the work being performed in the practical, to be submitted at the beginning of the subsequent tutorial.

    Final project and report (total of 40%)
    Each student will perform a complete transcriptomics analysis on a large dataset. Initially, a pilot/exploratory/feasibility study will be performed and submitted as a final project progress report submitted for assessment. This submission will include assessment of needed computational resources, a preliminary data quality assessment and will be allow the appropriateness of the project to be safely assessed prior to undertaking the major task.

    The final assessment task would be the submission of a complete analysis in the form of an executable R notebook (or other language if appropriate) including figures, code segments and natural language explanation, and with an executive summary of 300 words.
    Submission
    If an extension is not applied for, or not granted then a penalty for late submission will apply. A penalty of 10% of the value of the assignment for each calendar day that the assignment is late (i.e. weekends count as 2 days), up to a maximum of 50% of the available marks will be applied. This means that an assignment that is 5 days late or more without an approved extension can only receive a maximum of 50% of the marks available for that assignment.
    Course Grading

    Grades for your performance in this course will be awarded in accordance with the following scheme:

    M10 (Coursework Mark Scheme)
    Grade Mark Description
    FNS   Fail No Submission
    F 1-49 Fail
    P 50-64 Pass
    C 65-74 Credit
    D 75-84 Distinction
    HD 85-100 High Distinction
    CN   Continuing
    NFE   No Formal Examination
    RP   Result Pending

    Further details of the grades/results can be obtained from Examinations.

    Grade Descriptors are available which provide a general guide to the standard of work that is expected at each grade level. More information at Assessment for Coursework Programs.

    Final results for this course will be made available through .

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    SELTs are an important source of information to inform individual teaching practice, decisions about teaching duties, and course and program curriculum design. They enable the 最新糖心Vlog to assess how effectively its learning environments and teaching practices facilitate student engagement and learning outcomes. Under the current SELT Policy (http://www.adelaide.edu.au/policies/101/) course SELTs are mandated and must be conducted at the conclusion of each term/semester/trimester for every course offering. Feedback on issues raised through course SELT surveys is made available to enrolled students through various resources (e.g. MyUni). In addition aggregated course SELT data is available.

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  • Policies & Guidelines
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