最新糖心Vlog

PHARM 3102 - Drug Discovery & Development

North Terrace Campus - Semester 2 - 2025

This course will provide students with a fundamental knowledge of drug discovery and development from both a preclinical and clinical perspective. This includes approaches to sourcing and developing new drugs, from natural sources through to rational drug design, as well as approaches to testing drug efficacy and safety in both preclinical phases and in clinical trials. Additional topics in commercialisation provide students with a comprehensive knowledge of drug discovery and development, from bench to bedside.

  • General Course Information
    Course Details
    Course Code PHARM 3102
    Course Drug Discovery & Development
    Coordinating Unit Medical Sciences
    Term Semester 2
    Level Undergraduate
    Location/s North Terrace Campus
    Units 3
    Contact Up to 4 hours per week
    Available for Study Abroad and Exchange Y
    Prerequisites HLTH SC 2104
    Assumed Knowledge PHARM 2400
    Assessment Students will complete online quizzes, 2 mid-semester tests (one online), participate in tutorials and engage in workshops. There will be an end of course closed-book examination.
    Course Staff

    Course Coordinator: Dr Scott Smid

    Dr Scott Smid
    Dr Ian Musgrave
    Professor Sepehr Shakib
    Professor Andrew Somogyi
    Dr Daniel Barratt
    Associate Professor Betty Sallustio
    Dr Abdallah Salem
    Mr Greg MacPherson
    Course Timetable

    The full timetable of all activities for this course can be accessed from .

    A full course timetable can be accessed on MyUni.
  • Learning Outcomes
    Course Learning Outcomes
    1. Compare and understand common natural sources of drugs and contemporary approaches to drug design and development
    2. Demonstrate an understanding of the timelines and resources required to discover and develop new drugs in a preclinical setting
    3. Demonstrate an understanding of the critical features of each stage of the preclinical drug development process
    4. Demonstrate an understanding of the critical features of each stage of the clinical trials process for new drugs
    5. Work in small groups to profile a drug's preclinical and clinical discovery and development journey
    6. Demonstrate an understanding of the environment and drivers of drug discovery and commercialisation of research
    7. Demonstrate an understanding of population, gender and ethnic differences in drug action and metabolism
    最新糖心Vlog Graduate Attributes

    This course will provide students with an opportunity to develop the Graduate Attribute(s) specified below:

    最新糖心Vlog Graduate Attribute Course Learning Outcome(s)

    Attribute 1: Deep discipline knowledge and intellectual breadth

    Graduates have comprehensive knowledge and understanding of their subject area, the ability to engage with different traditions of thought, and the ability to apply their knowledge in practice including in multi-disciplinary or multi-professional contexts.

    1,2,6

    Attribute 2: Creative and critical thinking, and problem solving

    Graduates are effective problems-solvers, able to apply critical, creative and evidence-based thinking to conceive innovative responses to future challenges.

    4-6

    Attribute 3: Teamwork and communication skills

    Graduates convey ideas and information effectively to a range of audiences for a variety of purposes and contribute in a positive and collaborative manner to achieving common goals.

    5

    Attribute 4: Professionalism and leadership readiness

    Graduates engage in professional behaviour and have the potential to be entrepreneurial and take leadership roles in their chosen occupations or careers and communities.

    1-6

    Attribute 5: Intercultural and ethical competency

    Graduates are responsible and effective global citizens whose personal values and practices are consistent with their roles as responsible members of society.

    5,6,7

    Attribute 6: 最新糖心Vlogn Aboriginal and Torres Strait Islander cultural competency

    Graduates have an understanding of, and respect for, 最新糖心Vlogn Aboriginal and Torres Strait Islander values, culture and knowledge.

    7

    Attribute 7: Digital capabilities

    Graduates are well prepared for living, learning and working in a digital society.

    4,5

    Attribute 8: Self-awareness and emotional intelligence

    Graduates are self-aware and reflective; they are flexible and resilient and have the capacity to accept and give constructive feedback; they act with integrity and take responsibility for their actions.

    1-5
  • Learning Resources
    Required Resources
    Basic Principles of Drug Discovery and Development by Benjamin E Blass, 2015: ISBN 978-0-12-411508-8 is available online from the Barr Smith Library. This is probably the best online resource and freely accessible for students. Chapters can be downloaded.
    Recommended Resources
    Supplemental textbooks to be made available within BSL:

    Preclinical Development Handbook, Shayne Cox Gad (Editor). ISBN: 978-0-471-21383-3

    Textbook of Drug Design and Discovery. CRC Press. ISBN 9781420063226.

    Case Studies in Modern Drug Discovery and Development. Eds: Huang & Aslanian. 2012. Online ISBN:978111821968. This is also available online from the Barr Smith Library.

    Rang H.P et al. Pharmacology, 9th Ed., 2018, Churchill-Livingstone. This textbook has limited content pertaining to this course. Some chapters may be useful for reference, include pharmacokinetics, pharmacogenomics, drug development and drug toxicity.
    Online Learning
    The primary means of communication outside of the formal contact hours will be via Canvas. Announcements will be used as the main method of communicating with the student cohort. Course material will be supported by online resources, with lecture recordings, tutorial materials and on-line quizzes via Canvas. Material will be sequentially released in line with the teaching and learning activities in each week.
  • Learning & Teaching Activities
    Learning & Teaching Modes
    Lectures will be supported by problem-solving tutorials to reinforce and further expand or develop material covered in lectures. The nominated assignment is in small group format and is facilitated in workshops.
    Workload

    The information below is provided as a guide to assist students in engaging appropriately with the course requirements.

    Students are reminded that the overall workload for a full time student as stated in the 最新糖心Vlog of Adelaide Calendar is an average of 48 hours per week per teaching period (i.e. semester). This includes contact and non-contact hours and includes general study and research time for assignments. This course is a 3 unit course and thus represents quarter of a full time load. You should thus be putting in an average of 12 hours of study each week (including contact hours) for this course.
    Learning Activities Summary
    Overview to drug discovery and preclinical development: small molecule and biologics
    Conventional and historical approaches to drug discovery
    Basic and applied pharmacokinetic concepts in drug development
    Biotransformation: implications for drug development
    Pharmacogenomic considerations in drug development
    Drug discovery: Identifying drug targets
    Sources for drug discovery: Bioprospecting
    Rational drug design
    Drug repurposing
    Preclinical drug screening; In vitro and in vivo models
    Assessment of toxicology in preclinical drug development
    Clinical Trials overview: Phase I-IV studies
    Commercialisation approaches: academic and industry perspectives
    Specific Course Requirements
    N/A
  • Assessment

    The 最新糖心Vlog's policy on Assessment for Coursework Programs is based on the following four principles:

    1. Assessment must encourage and reinforce learning.
    2. Assessment must enable robust and fair judgements about student performance.
    3. Assessment practices must be fair and equitable to students and give them the opportunity to demonstrate what they have learned.
    4. Assessment must maintain academic standards.

    Assessment Summary

    Online quizzes, tutorial and workshop participation, summative tests, assigned drug development project and final exam
    Assessment Detail
    Assessment Task Task Type Due Weighting Course Learning Outcomes assessed
    Test 1: MCQ and short answer test on all lecture and tutorial content weeks 1-6 inclusive, Summative

    Week 8

    15%
    Test 2: Written MCQ test on all lecture and tutorial content weeks 7-12 inclusive Summative Week 12 15%
    Project: Students work in small groups to write a report on an assigned drug and target. Students provide a written report on completion and group presentation. Summative Week 12 30%
    Examination.
    A 2.5 hour exam
    Summative End of Semester 40%
    Submission
    Coursework submissions (e.g. Written Assignments/projects) received after the deadline will be penalised as follows:10% of total
    available points will be penalised per day (24 hour period or fraction thereof).
    An automatic zero mark will be applied after 7 days.
    If you miss a coursework assessment test e.g. from illness, you are required to
    present medical or compassionate certification to be eligible to sit a
    supplementary test. Such certificates need to be provided to The Course
    Coordinator directly within one week of the test date. The date
    and time of the test is then determined by the Course Coordinator
    and is not negotiable. Eligible students will be informed of the supp. test date
    by email.
    Course Grading

    Grades for your performance in this course will be awarded in accordance with the following scheme:

    M10 (Coursework Mark Scheme)
    Grade Mark Description
    FNS   Fail No Submission
    F 1-49 Fail
    P 50-64 Pass
    C 65-74 Credit
    D 75-84 Distinction
    HD 85-100 High Distinction
    CN   Continuing
    NFE   No Formal Examination
    RP   Result Pending

    Further details of the grades/results can be obtained from Examinations.

    Grade Descriptors are available which provide a general guide to the standard of work that is expected at each grade level. More information at Assessment for Coursework Programs.

    Final results for this course will be made available through .

  • Student Feedback

    The 最新糖心Vlog places a high priority on approaches to learning and teaching that enhance the student experience. Feedback is sought from students in a variety of ways including on-going engagement with staff, the use of online discussion boards and the use of Student Experience of Learning and Teaching (SELT) surveys as well as GOS surveys and Program reviews.

    SELTs are an important source of information to inform individual teaching practice, decisions about teaching duties, and course and program curriculum design. They enable the 最新糖心Vlog to assess how effectively its learning environments and teaching practices facilitate student engagement and learning outcomes. Under the current SELT Policy (http://www.adelaide.edu.au/policies/101/) course SELTs are mandated and must be conducted at the conclusion of each term/semester/trimester for every course offering. Feedback on issues raised through course SELT surveys is made available to enrolled students through various resources (e.g. MyUni). In addition aggregated course SELT data is available.

  • Student Support
  • Policies & Guidelines
  • Fraud Awareness

    Students are reminded that in order to maintain the academic integrity of all programs and courses, the university has a zero-tolerance approach to students offering money or significant value goods or services to any staff member who is involved in their teaching or assessment. Students offering lecturers or tutors or professional staff anything more than a small token of appreciation is totally unacceptable, in any circumstances. Staff members are obliged to report all such incidents to their supervisor/manager, who will refer them for action under the university's student鈥檚 disciplinary procedures.

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