最新糖心Vlog

Name	Role	Building/Room	Email
Assoc. Prof. Chris Ford	Course Coordinator	WIC 4.43, Waite Campus	christopher.ford@adelaide.edu.au
Dr Cindy Bottema	Lecturer assisting	G15, JS Davies Building, Roseworthy Campus	cynthia.bottema@adelaide.edu.au
Dr Beth Loveys	Teaching	G26, Charles Hawker Building, Waite Campus	beth.loveys@adelaide.edu.au

1	Describe the role of thermodynamics in the determination of biochemical reactivity and differentiate between the kinetic and thermodynamic factors influencing biochemical reactions.
2	Explain how protein structure and function is derived from the constituent amino acids, and compare the features of structural and globular proteins.
3	Describe the basic principles governing the rate of enzyme catalysed reactions and the forms of inhibition of enzyme-catalysed reactions.
4	Describe the major pathways of carbohydrate and lipid metabolism and demonstrate how energy is stored and released through them.
5	Explain how the functional diversity of lipids is derived from their composition.
6	Describe the basic features of the cellular metabolism of amino acids and nucleic acids.
7	At the end of this course, students will have demonstrated familiarity and competence with the practical skills and techniques used in biochemical research and analysis. This will include experimental planning, the preparation of reagents and use of basic instrumentation (spectrophotometers, centrifuges, chromatographic apparatus etc), the collection of biochemical data and its presentation, and most importantly, the analysis and interpretation of the outcomes of biochemical investigations.
8	At the end of this course, students will have demonstrated the ability to undertake the research, preparation and delivery of presentations of biochemical topics selected to reinforce and augment the material presented in lectures.

There is no required textbook for this course.

The recommended text for this course is Tymoczko, Stryer and Berg (2015) Biochemistry A Short Course 3^rd Edition. 

Advanced treatment of topics covered during the course will be found in many of the major undergraduate biochemical textbooks. Students seeking further details and greater coverage of topics than are provided by the recommended text are encouraged to consider supplementing their study using one of these. Other good biochemistry texts include:

• Nelson and Cox (2012) Lehninger’s Principles of Biochemistry 6^th Edition
• Berg, Tymoczko and Stryer (2006) Biochemistry 6^th Edition
• Mathews, Van Holde and Ahern (2000) Biochemistry.

A limited number of copies of some of these texts will be held on Reserve in the Waite library.

The publisher (WH Freeman and Company) offers a range of eBook options for access to the texts by Tymoczko et al., Berg et al. and Nelson & Cox. Some of these may be available for use by 最新糖心Vlogn students

A shorter biochemistry ebook suitable for Kindle readers or the Kindle App on iPads etc, Instant Notes in Biochemistry 2^nd Edition, by David Hames, is available for purchase or short-term rental from the Kindle store. While this book does not cover topics in the depth provided by any of the major textbooks mentioned above, it nonetheless provides a useful background to all of the topics covered in the course.

 A reading list of references relevant to topics covered in the course, which in many instances will provide the research context around these topics, is provided and can be accessed from MyUni. Individual articles contained on the reading list may be downloaded for private study. From time to time during the course, lecturing staff, tutors etc may suggest that you read additional scientific papers. These will be made available for online reading and download via MyUni; full details will be given as appropriate.

MyUni: Teaching materials and course documentation will be posted on the MyUni website ().

Course administration is accomplished using MyUni: activities will include email, Announcements, lecture handouts and recordings, an online reading list and links to past examinations. Coursework assignments may be submitted through Turnitin as directed. Coursework marks will be made available through the Gradebook. Assessment in the form of online quizzes will be offered during the semester as a part of the Formative Assessment component.  All materials will be released at the relevant time during the semester.

Online activities for use before practical classes will be delivered using MyUni.

Lectures:

There are three lectures (each of 1 hour duration) per week; the first hour of lectures may be used to revise the previous week's lecture material.

Lecture notes may be posted to MyUni a few days in advance of the respective lecture and will not generally be provided to students in hard copy. Every attempt will be made to record lectures, and to make them available for streaming and download from MyUni.

A student enrolled in a 3 unit course, such as this, should expect to spend, on average 12 hours per week on the studies required. This includes both the formal contact time required to the course (e.g., lectures and practicals), as well as non-contact time (e.g., pre-class preparation, post-class assessments, reading and revision).

Schedule

Week	Type of learning activity	Topic
Week 1	Lecture	Course introduction; Biochemistry in Context: basic principles of biochemical activity – 1 lecture. Protein structure and function - 1 lectures.
	Practical	Analysis of nitrite.
	Tutorial or other activity	Biochemical calculations. Protein structure and function.
Week 2	Lecture	Protein structure and function revisited  – 1 lecture; Enzyme structure and function - 1 lectures.
	Practical	Analysis of nitrite.
	Tutorial or other activity	Biochemical calculations. Protein structure and function.
Week 3	Lecture	Online test - 1 lecture. Enzyme revision- 1 lecture
	Practical	Enzyme kinetics.
	Tutorial or other activity	Enzymes.
Week 4	Lecture	Lipid biochemistry- 2 lectures.
	Practical	Enzyme kinetics.
	Tutorial or other activity	Enzymes.
Week 5	Lecture	Lipid revision- 1 lectures. Haemoglobin and myoglobin - 1 lecture.
	Practical	Ion exchange chromatography.
	Tutorial or other activity	Lipids.
Week 6	Lecture	Carbohydrates - an introduction - 1 lectures; polysaccharides: biofuels and human health - 1 lecture.
	Practical	Ion exchange chromatography.
	Tutorial or other activity	Lipids.
Week 7	Lecture	No lectures ANZAC DAY
	Practical	No lecture ANZAC DAY
	Tutorial or other activity	No tutorial ANZAC DAY
Week 8	Lecture	Carbohydraterevision - 1 lecture. Introduction to metabolism - 1 lectures.
	Practical	Glucose extraction and analysis.
	Tutorial or other activity	Carbohydrates
Week 9	Lecture	Glycolysis - 1 lecture. Pathways to the production of low-alcohol wines - 1 lecture.
	Practical	Glucose extraction and analysis.
	Tutorial or other activity	Carbohydrates.
Week 10	Lecture	Metabolism and the glycolysis pathway revisited - 1 lecture. Beta oxidation of lipids- 1 lecture.
	Practical	Starch extraction and analysis.
	Tutorial or other activity	Metabolism.
Week 11	Lecture	The TCA cycle and oxidative phosphorylation - 2 lectures.
	Practical	Starch extraction
	Tutorial or other activity	Metabolism
Week 12	Lecture	TCA cycle and oxidative phosphorylation revisited - 1 lecture. Amino acid and nucleic acid metabolism - 1 lectures.
	Practical	Team Based Learning activity 2 (whole class).
	Tutorial or other activity	Team Based Learning activity 2 (whole class).

PRACTICAL SESSION CODE OF CONDUCT All students must follow these rules in practical exercises:

• Our students are from many countries, and speak in many different languages. The language of tuition and assessment of all courses at the 最新糖心Vlog of Adelaide is English. Our teaching and demonstrating staff work exclusively in English and it is vital therefore that all discussion and communication between students in all class situations is in English ONLY. This is of particular importance with respect to laboratory classes, in which the Health, Safety and Wellbeing of all participants are at all times the most important consideration. It is expected that ALL students will be respectful and understanding of the diversity of language skills possessed by class members, and where appropriate will provide explanation and guidance to peers.
• No eating, drinking, application of makeup, etc in laboratories; no water bottles or items of food or drink may be visible in laboratories; mobile phone calls to be taken and made outside the laboratory only.
• Closed shoes must be worn at all times in all practical exercises, wherever they are held.
• Lab coats and other personal protective equipment must be worn at all times in laboratories or other areas whenever students are instructed to wear them; these should be removed when leaving the laboratory.
• Bags, coats, etc. that are brought into a lab must be placed under the bench to avoid causing obstructions.
• All containers used during a practical session must be labelled, including water and other common non-toxic substances.
• Report all accidents, personal or involving experimental materials, to the person in charge.
• Playing around in a laboratory and many other work areas is dangerous; participants in improper behaviour will be asked to leave.
• Students must dispose of materials as directed.
• Students must wash their hands upon departing the labs and other work areas.
• Students must clean and tidy their bench and/or work area before departure; benches and/or work areas will be inspected at the end of each practical session.
• Students not complying with the rules will not receive credit for the practical session in which the breach occurred.

No elements of the course have a formal exemption from the requirements of the Assessment for Coursework Programs Policy.

Assessment task	Task type	Due	Weighting	Learning Outcome
Practical report - starch extraction	Summative/Formative	Week 11 or 12	10%	7
Practical skills and biochemical calculations - Online test	Summative/Formative	Week 3	7.5%	7
Laboratory notebook	Summative/Formative	Week 12 or 13	10%	7
Online quizzes	Summative/Formative	Ongoing during semester	7.5%	1,2,3,4,5,6
Tutorials	Summative/Formative	Weeks 1 or 2, 3 or 4, 5 or 6 and 9 or 10	5%	1 to 6; 8
Team-Based-Learning	Summative/Formative	Weeks 11 and 12	10%	2,3,4,8
Exam	Summative		50%	4,6

Coursework formative and summative assessment - details:

Formative and summative assessment for the course will be covered by the following items:

Practical class reports, laboratory book presentation and online test (27.5%):
a. There will be five practical classes conducted per student over the course of the semester. Each of these will incorporate assessment of work, submitted as laboratory notebook or a formal report write-up (carbohydrate analysis practical classes).
All submitted work will be returned with feedback within 2 weeks of submission.

b. You will be supplied with a laboratory notebook and detailed instructions on its use. The notebooks will be checked at intervals during the course and assessed in weeks 12 or 13. The marks awarded for the laboratory notebook will be added to those for the practical assessments.

c. An online test will be held during the first lecture period in week 3. The test will comprise questions covering the biochemical calculations and basic practical skills encountered in weeks 1 and 2.

Online quizzes (7.5%)
Duringthe semester, weekly online quizzes will be set from within MyUni/Assessments. Each quiz will contain between 5-10 questions, which will comprise a number of formats including but not limited to multiple choice, missing words, ordering
and calculations. Quizzes will normally be available immediately after the lecture until midnight (to test recall) and then again 24 hours after the lecture (to test understanding and improve retention)

Thequizzes are intended to provide each student with a brief assessment of their knowledge of topics covered in recent and past lectures and tutorials. Each quiz may be attempted only once; you will receive full answers upon completion of the quiz.

Tutorial assessments (5%):
Tutorial classes will be held in weeks 1 or 2, 3 or 4, 5 or 6, 7 or 8, 9 or 10. You will attend tutorials in the weeks when you are not scheduled for practical classes. The tutorial classes will comprise two one-hour sessions. In the first of these ('reinforcement tutorials') you will be required to provide answers to questions, provided through MyUni a week before your class, based on material covered in the relevant earlier lectures. Full details will be provided in week 1 or 2 as appropriate. The second session ('extension tutorials') will seek to guide you to an in-depth understanding of the topic, through a series of short class-based discussion questions designed to extend the knowledge gained in the lectures.

Team Based Learning (TBL)(10%):
There will also be one whole-class Team Based Learning (TBL) exercises during the semester, in which you will be provided with some learning materials prior to the class that will provide you with the background knowledge for the TBL topic under consideration. The TBL class itself will begin with a series of 'single-best-answer' questions based on the pre-class learning material, which will be answered individually by each of you. You will then join your team members, and working together, provide answers to the same SBA questions. The answers will be revealed and an opportunity for discussion and clarification of
any areas of confusion will occur. Subsequently, still working in your teams, you will be presented with a series of SBA questions based on one or more scenarios developed from the topics under study, and will provide answers to these in a class-based setting.
 
Summative (examination-based) Assessment - details:

Final Exam (50%):
The final examination in the Semester 1 exam period will consist of a 3-hour paper, containing questions derived from lectures delivered in weeks1-12 and the associated tutorials. All questions must be answered.

Late submission of assessments

If an extension is not applied for, or not granted then a penalty for late submission will apply. A penalty of 10% of the value of the assignment for each calendar day that is late (i.e. weekends count as 2 days), up to a maximum of 50% of the available marks will be applied. This means that an assignment that is 5 days or more late without an approved extension can only receive a maximum of 50% of the mark.