GENETICS 3210 - Advanced Molecular Biology IIIB (Genetics)

North Terrace Campus - Semester 2 - 2017

The material taught in this courses is organised around the theme of genes ? how genes function and their roles in development and disease. The aim is to give students an appreciation, at an advanced level, of the mechanisms that control gene expression, the genetic determination of developmental pathways, the various types of human genetic mutation that lead to disease and the pathogenic pathways from genotype to phenotype. The practical component of the course will extend students? familiarity with various laboratory and/or analytical techniques used in human and developmental genetics. It includes a specialised set of Problem Based Learning (PBL)/Tutorial exercises, which are designed to provide students with a perspective of how cutting edge molecular biology principles and techniques are applied to major research questions. The PBL segment of the course may include aspects of biochemistry, genetics, microbiology, immunology and chemistry. This course will illustrate that cross-disciplinary approaches are essential in modern research.

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Course Details

Course Code	GENETICS 3210
Course	Advanced Molecular Biology IIIB (Genetics)
Coordinating Unit	School of Biological Sciences
Term	Semester 2
Level	Undergraduate
Location/s	North Terrace Campus
Units	6
Contact	Up to 12 hours per week
Available for Study Abroad and Exchange	N
Prerequisites	BIOCHEM 2510 & BIOCHEM 2520 & GENETICS 2510 & GENETICS 2520
Incompatible	Genetics 3211 and Genetics 3212 and Genetics 3520
Restrictions	Available to BSc(MolBiol) students only
Assessment	Final Exam, Literature review, Research report, PBL, MCQ Exam

Course Staff

Course Coordinator: Associate Professor Michael Lardelli

Course Timetable

The full timetable of all activities for this course can be accessed from .

Course Learning Outcomes

The course aims to give students a level of understanding of concepts and experimental techniques in the areas of gene regulation, developmental genetics and human genetics that would enable them to develop competencies expected of a university graduate in Genetics. The course cannot hope to cover comprehensively the very broad range of research questions in these areas but it will give students understanding of specific exemplary questions and provide them with knowledge of how they can extend their learning as required by future studies and employment. The practical aspect of the course aims to equip students with sufficient fundamental skills to apply them to a broad range of positions requiring these skills. The Problem Based Learning (PBL) exercises aim to give students a perspective of how cutting edge molecular biology principles and techniques are applied to major research questions.

The anticipated knowledge, skills and/or attitude to be developed by the student are:

1	Understanding of the underlying conceptual framework regarding the regulation of genes and how research expands our knowledge in this area
2	Understanding of the underlying conceptual framework regarding how genes control embryo development and how research expands our knowledge in this area
3	Understanding of the underlying conceptual framework regarding human genetics and how research expands our knowledge in this area
4	Comprehension of scientific research data described in peer-reviewed journals
5	Recording of laboratory research notes and analysis and reporting of experimental data
6	The ability to extract relevant information from literature databases and to present it in written form
7	To provide students with the opportunity to derive and interpret novel experimental outcomes in a supportive environment commensurate with their capabilities as a final year candidates for the Degree of Bachelor of Science (Molecular Biology).

最新糖心Vlog Graduate Attribute	Course Learning Outcome(s)
Deep discipline knowledge informed and infused by cutting edge research, scaffolded throughout their program of studies acquired from personal interaction with research active educators, from year 1 accredited or validated against national or international standards (for relevant programs)	1, 2, 3, 4, 5, 6, 7
Critical thinking and problem solving steeped in research methods and rigor based on empirical evidence and the scientific approach to knowledge development demonstrated through appropriate and relevant assessment	4, 5, 6, 7
Teamwork and communication skills developed from, with, and via the SGDE honed through assessment and practice throughout the program of studies encouraged and valued in all aspects of learning	7
Career and leadership readiness technology savvy professional and, where relevant, fully accredited forward thinking and well informed tested and validated by work based experiences	4, 5, 6, 7
Self-awareness and emotional intelligence a capacity for self-reflection and a willingness to engage in self-appraisal open to objective and constructive feedback from supervisors and peers able to negotiate difficult social situations, defuse conflict and engage positively in purposeful debate	4, 5, 6, 7

Learning & Teaching Modes

This course will be delivered by the following means:

“Pre-workshop” material in the form of pre-recorded lectures or assigned reading material etc. 10 hours per week (includes revision of delivered material).

4 workshops of 1 hour each per week. Each week will include one 20 minute in-workshop summative test.

12 hours of practical laboratory/placement per fortnight (weeks 1-6)
(Note: Students who do not obtain a laboratory placement will perform the normal Practical course of Genetics 3211 in weeks 1-6)

6 PBL sessions of up to 5 hours per week in weeks 7-12.

Workload

The information below is provided as a guide to assist students in engaging appropriately with the course requirements.

A student enrolled in a 6 unit course, such as this, should expect to spend, on average 24 hours per week on the studies required. This includes both the formal contact time required to the course (e.g., lectures and practicals), as well as non-contact time (e.g., reading and revision).

Learning Activities Summary

	Type of learning activity	Topic
Week 1	Pre-workhop material	Developmental Neurogenetics
	Worskhop	Developmental Neurogenetics
	Practical	Laboratory Placement or Developmental Genetics Practical
Week 2	Pre-workhop material	Developmental Neurogenetics
	Worskhop	Developmental Neurogenetics
	Practical	Laboratory Placement or Developmental Genetics Practical
Week 3	Pre-workhop material	Developmental Neurogenetics
	Worskhop	Developmental Neurogenetics
	Practical	Laboratory Placement or Developmental Genetics Practical
Week 4	Pre-workhop material	Developmental Genetics
	Worskhop	Developmental Genetics
	Practical	Laboratory Placement or Developmental Genetics Practical
Week 5	Pre-workhop material	Regulation of Gene Expression / Epigenetics
	Worskhop	Regulation of Gene Expression / Epigenetics
	Practical	Laboratory Placement or alternative practical work
Week 6	Pre-workhop material	Regulation of Gene Expression / Epigenetics
	Worskhop	Regulation of Gene Expression / Epigenetics
	Practical	Laboratory Placement or alternative practical work
Week 7	Pre-workhop material	Regulation of Gene Expression / Epigenetics and Cancer Genetics
	Worskhop	Regulation of Gene Expression / Epigenetics and Cancer Genetics
	Practical	Problem Based Learning Exercises
Week 8	Pre-workhop material	Plant Developmental Genetics
	Worskhop	Plant Developmental Genetics
	Practical	Problem Based Learning Exercises
Mid Semester Break
Week 9	Pre-workshop material	Human Genetics
	Worskhop	Human Genetics
	Practical	Problem Based Learning Exercises
Week 10	Pre-workhop material	Human Genetics
	Worskhop	Human Genetics
	Practical	Problem Based Learning Exercises
Week 11	Pre-workhop material	Human Genetics
	Worskhop	Human Genetics
	Practical	Problem Based Learning Exercises
Week 12	Pre-workhop material	Human Genetics
	Worskhop	Human Genetics
	Practical	Problem Based Learning Exercises
Week 13*	Pre-workhop material
	Worskhop
	Practical

The 最新糖心Vlog's policy on Assessment for Coursework Programs is based on the following four principles:

Assessment must encourage and reinforce learning.
Assessment must enable robust and fair judgements about student performance.
Assessment practices must be fair and equitable to students and give them the opportunity to demonstrate what they have learned.
Assessment must maintain academic standards.

Assessment Summary

Assessment task	Type of assessment	Percentage of total assessment for grading purposes #	Hurdle Yes or No #	Outcomes being assessed / achieved
In-Workshop Tests	Formative / Summative	15%	No	1, 2, 3, 4
Final Examination	Summative	40%	No	1, 2, 3, 4
Laboratory Placement/Practical	Formative / Summative	25%	No	4, 5, 6, 7
PBL	Formative / Summative	20%	No	4, 6, 7

Assessment Detail

Laboratory Placement (25% of total course grade, learning objectives 4, 5, 6, 7) - comprised of one 10-15 minute oral presentation (5%), laboratory performance (7.5%) and written practical report (12.5%) in weeks 1-6. Marked Practical Reports will be handed in at the end of week 6 and promptly assessed by mentors/demonstrators to provide feedback to students and a sense of progressive accomplishment in the course. Students who do not obtain a laboratory placement will perform the normal Practical course of Genetics 3211 for weeks 1-6 and will be assessed as for that course.

PBL exercises, including assessment via 2 small group oral presentations, weeks 7-12: (20% of total course grade, learning objectives 4, 6, 7). Each individual in the PBL group marked separately.

Examinations in workshops (15% of course grade, Learning Objectives 1, 2, 3, 4). The final third of one workshop session per week (any of the four sessions per week) will be devoted to answering a series of questions assessing material in that and previous workshops and the pre-workshop material. This will test and reinforce students’ understanding of the course material. To avoid problems with students occasionally missing workshops, students’ final accumulated mark for these examinations will be made up of their best 8 scores (from the possible 12 examinations).

Final examination (40% of course grade, learning objectives 1, 2, 3, 4). This will be a three hour examination assessing any/all theoretical aspects of the course. The examination includes compulsory areas but also a limited choice of questions within each compulsory area.

Submission

Details on submission are provided in the Course Handbook and/or Practical manuals etc.

Late submission of assessments:

If an extension is not applied for, or not granted then a penalty for late submission will apply. A penalty of 10% of the value of the assignment for each calendar day that is late (i.e. weekends count as 2 days), up to a maximum of 50% of the available marks will be applied. This means that an assignment that is 5 days or more late without an approved extension can only receive a maximum of 50% of the mark.

Course Grading

Grades for your performance in this course will be awarded in accordance with the following scheme:

M10 (Coursework Mark Scheme)
Grade	Mark	Description
FNS		Fail No Submission
F	1-49	Fail
P	50-64	Pass
C	65-74	Credit
D	75-84	Distinction
HD	85-100	High Distinction
CN		Continuing
NFE		No Formal Examination
RP		Result Pending

Further details of the grades/results can be obtained from Examinations.

Grade Descriptors are available which provide a general guide to the standard of work that is expected at each grade level. More information at Assessment for Coursework Programs.

Final results for this course will be made available through .

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SELTs are an important source of information to inform individual teaching practice, decisions about teaching duties, and course and program curriculum design. They enable the 最新糖心Vlog to assess how effectively its learning environments and teaching practices facilitate student engagement and learning outcomes. Under the current SELT Policy (http://www.adelaide.edu.au/policies/101/) course SELTs are mandated and must be conducted at the conclusion of each term/semester/trimester for every course offering. Feedback on issues raised through course SELT surveys is made available to enrolled students through various resources (e.g. MyUni). In addition aggregated course SELT data is available.
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Policies & Guidelines
This section contains links to relevant assessment-related policies and guidelines - all university policies.
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Students are reminded that in order to maintain the academic integrity of all programs and courses, the university has a zero-tolerance approach to students offering money or significant value goods or services to any staff member who is involved in their teaching or assessment. Students offering lecturers or tutors or professional staff anything more than a small token of appreciation is totally unacceptable, in any circumstances. Staff members are obliged to report all such incidents to their supervisor/manager, who will refer them for action under the university's student鈥檚 disciplinary procedures.

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Authorised by:	Deputy Vice-Chancellor and Vice-President (Academic)
Maintained by:	Course Outlines Administrator

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